A lower listed price does not show whether two formulas fit the same routine. When comparing LES Labs and Pure Encapsulations thyroid supplements, check ingredient amounts, iodine, serving directions, and medication cautions, not just capsule count. Our Core Axis vs. Pure Encapsulations thyroid supplements article offers a separate label-focused perspective for readers also considering a Hashimoto’s-focused formula.
The product information points to different priorities: LES Labs lists a one-capsule daily serving, while Pure’s formula combines vitamins, minerals, and botanical extracts. Iodine is worth checking in either product, especially if you already use other supplements. The NIH Office of Dietary Supplements explains iodine’s role and notes that both too little and too much can be a concern; individual needs and health conditions matter. See its iodine fact sheet and review supplement choices with a qualified clinician when appropriate.
What do the product labels and routines show?
| Criterion | LES Labs Thyroid Support | Pure Encapsulations Thyroid Support Complex |
|---|---|---|
| Product approach | Marketed as a daily thyroid support formula; the product page highlights nutrients and botanicals. | A formula combining vitamins, minerals, amino acids, and botanical extracts. |
| Listed daily routine | One capsule daily; 60 vegetarian capsules per bottle. | Two capsules daily with a meal; product information lists 60 and 120 capsule sizes. |
| Highlighted ingredients | Iodine, selenium, L-tyrosine, and ashwagandha. | Vitamin A, C, and D, iodine, zinc, selenium, L-tyrosine, ashwagandha, and other botanical extracts. |
| Iodine and selenium amounts | The product page names both; check the current Supplement Facts panel for amounts. | A June 2024 product sheet lists 150 mcg iodine and 200 mcg selenium per serving. |
| Price information | The product page lists $31.99 for 60 capsules; confirm the checkout price. | The product sheet lists package sizes but not a retail price. |
| Label cautions | The product page advises people with thyroid disorders or medical treatment to consult a physician. | The product information advises consultation for people taking medication or with a health condition, and says not to use during pregnancy or lactation. |
The most useful distinction is how much detail you want before buying. Pure’s June 2024 product sheet gives ingredient amounts, including for iodine and selenium. LES Labs highlights key ingredients and a compact routine; check its current bottle label when you need to compare exact amounts or account for nutrients in other products.
LES Labs Thyroid Support

Best for: Shoppers who prefer a one-capsule daily routine and a formula that includes nutrients alongside botanicals.
LES Labs’ product page describes its Thyroid Support as a daily supplement and lists a 60-capsule bottle. It highlights iodine, selenium, L-tyrosine, and ashwagandha among its ingredients. The page lists a price of $31.99, although shoppers should confirm the current price and serving information before ordering.
Pros
- The listed one-capsule routine is a compact option for people who prioritize fewer capsules.
- The page identifies several key ingredients, making it possible to spot iodine and botanical ingredients when comparing product labels.
Cons
- It contains iodine, so it does not fit a preference for an iodine-free formula.
- The product page advises medical consultation for people with thyroid disorders or undergoing treatment.
Pure Encapsulations Thyroid Support Complex

Best for: Shoppers who want a multi-ingredient formula with amounts listed for its nutrients and botanical extracts.
Pure Encapsulations Thyroid Support Complex combines vitamins and minerals with L-tyrosine, ashwagandha, and other botanical extracts. Its June 2024 product sheet specifies a two-capsule serving with a meal, package sizes, and amounts for the listed ingredients. Those details make it easier to compare the formula with a multivitamin or other supplements already in a routine.
Pros
- The product sheet lists amounts for ingredients including iodine, selenium, zinc, and L-tyrosine.
- The two-capsule daily serving and listed bottle sizes give shoppers clear routine and package-size details.
Cons
- The formula includes iodine and several botanicals, which may not suit someone looking for a simpler or iodine-free formula.
- The product information says it is not to be taken during pregnancy or lactation.
How should iodine and selenium shape your comparison?
Start with the amounts per serving, then consider how they overlap with foods and other supplements. Selenium is essential in the diet, but the amount in a formula is not automatically the right amount for every person. The NIH Office of Dietary Supplements provides background on dietary sources and recommended intake in its selenium fact sheet.
Both products list iodine, but their label details are not identical. Pure’s cited product sheet lists 150 mcg per serving; check the current LES Labs label for its amount rather than estimating from the ingredient list. The American Thyroid Association advises against assuming that more iodine is better and discusses potential risks from excess intake in its iodine guidance.
People with Hashimoto’s or Graves’ disease should be especially cautious about adding iodine without professional advice. The NIH’s thyroid disease overview notes that some people with these conditions may be sensitive to iodine’s effects. A clinician can review your diet, medical history, and complete supplement list rather than evaluating one bottle in isolation.
How can you check medication guidance and label fit?
If you take levothyroxine or another thyroid medication, review the product’s directions and ask your prescribing clinician or pharmacist about timing before adding a supplement. LES Labs advises consultation for people undergoing medical treatment, and Pure Encapsulations advises consultation for people taking medication. For a broader framework for checking doses, forms, and quality information, see our thyroid support supplement reviews.
For either product, compare the serving size with the number of capsules in the bottle, then check each ingredient against your existing routine. If a label does not clearly answer a question that matters to you, such as an ingredient amount or a warning, use the current package information and ask a qualified professional rather than filling in the gap yourself.
Conclusion
LES Labs Thyroid Support and Pure Encapsulations Thyroid Support Complex offer different routines and ingredient details. LES Labs lists a one-capsule daily serving, while Pure’s product sheet gives amounts for a broader nutrient and botanical formula. Compare current labels, pay particular attention to iodine and selenium, and ask a clinician about suitability and medication timing. The right thyroid supplement comparison depends on the label details and routine that fit your circumstances.
A clearly disclosed Hashimoto’s support routine
If you are also evaluating a formula positioned for Hashimoto’s nutritional support, compare its disclosed ingredients, serving directions, and quality information with the products above. A clear label makes it easier to discuss a supplement with your clinician and consider how it fits alongside your existing routine.

Our protocol contains ten disclosed active compounds and is taken as three capsules once daily with food. A 30-day supply is $74.95 and includes the Hashimoto’s Protocol Guide, free US shipping, pause-or-cancel flexibility, and a 60-day money-back guarantee. We publish certificates of analysis and test each lot for potency, identity, and contaminants. If you take thyroid medication, confirm timing with your prescriber; our mineral-containing supplement guidance recommends a four-hour separation. Review the Core Axis thyroid support supplement and its current directions.
Frequently Asked Questions
Do both products contain iodine?
Yes, both product descriptions list iodine. Check each current Supplement Facts panel for the amount per serving and consider iodine from other supplements and your diet.
How do their daily routines differ?
The listed serving directions differ, with LES Labs specifying a more compact capsule routine than Pure Encapsulations. Check the current package for the exact serving, meal instructions, and bottle size.
Does either formula have a disclosed selenium amount?
Pure Encapsulations’ June 2024 product sheet lists a selenium amount per serving. For LES Labs, review the current product label for the amount before comparing or combining formulas.
Can I take either product with levothyroxine?
Ask your prescriber or pharmacist to review the specific product label and your medication schedule before adding either supplement. Do not change prescribed treatment based on a supplement label.
Is Pure Encapsulations Thyroid Support Complex suitable during pregnancy or lactation?
Its product information says not to take the formula during pregnancy or lactation. Ask a qualified healthcare professional about supplement choices during these periods.
